Natural Sciences: Audrey Chung '26

Major(s) and minor(s)

B.S. Biology 

Minor in Ethics

Hometown

Victor, NY

Areas of interest/focus in research

Hematology/Oncology

One of the projects I have worked on was focused on analyzing cells of the tumor microenvironment (TME) in various indolent B-cell non-Hodgkin lymphomas. My job was to measure and analyze the presence of different surface markers on various types of white blood cells in splenectomy specimens from splenic lymphoma patients. The goal was to uncover the characteristics of TME cells to promote the development of non-invasive diagnostic procedures and precision therapies. 

I am currently working on a project dedicated to improving the analysis of macrophages involved in antibody-dependent cellular phagocytosis (ADCP), a process in which a cell engulfs antibody-coated targets. The project entails the comparison of data automatically generated via computer software to data manually collected through our own annotation software we have been developing. This helps us to assess the accuracy of automated programs needed for analyzing high content video files of ADCP, as understanding ADCP kinetics and mechanisms is necessary to improve treatments of hematological malignancies, such as chronic lymphocytic leukemia.

I am also currently working with the THP-1 cell line, specifically inducing differentiation of these cells into macrophages and assessing their ability to engage in ADCP visualized by live cell time-lapse video microscopy. These cells can be tested by interventions that may affect ADCP, including genetic modifications.

Labs / departments / offsite programs where research was conducted

About me...

Hi! My name is Audrey, and I’m a sophomore from Victor, NY studying biology at the University of Rochester. I’ve been working as a student intern in the Zent and Chu Lab since my freshman year, and I’ve grown very interested in the field of hematology and cancer research. I’m incredibly grateful for all of the opportunities my research position has provided me, and I hope to help other students find the best opportunities for themselves as a Research Ambassador.

How has your experience as a researcher influenced your career objectives?

While I still plan on pursuing medical school, my research experience has inspired me to stay involved in research beyond my undergraduate years. I think the interface between clinical research and medical practice is essential for discovering and providing the best patient care possible, and I hope to pursue a career path that allows me to work in both disciplines.

Campus organizations, programs, activities, clubs, awards/distinctions

Rigby Wile Prize (2023)

Schwartz Discover Grant (2023)

Friends of Strong Volunteer - Gastroenterology at Sawgrass, Pediatric Imagining at Golisano Children’s Hospital, and Child and Adolescent Psychiatry at URMC

Hospital Elder Life Program (HELP) Volunteer at Highland Hospital

University of Rochester Symphony Orchestra (URSO)

Korean Student Union

Dean’s List (all semesters)

Fun Fact: when I'm not doing research you can usually find me...

Listening to music or a podcast, going for a run, playing golf, reading, or watching a sunset.

Areas where I may be particularly helpful

• Contacting mentors and writing applications for new research positions
• Writing applications for the Schwartz Discover Grant or other research grants
• Preparing for presentations
• Academic advice

What advice do you have for prospective or new researchers?

I think getting started in research as an undergrad is a uniquely enriching experience that is only optimized when you take charge of it. Your experience is ultimately in your own hands, and you can only make the most of it when you find a field of research that you are genuinely passionate about. This does not mean that you have to navigate it on your own, though. There are many resources and people who are eager to help you in starting your research journey and providing guidance along the way.

Email me at: achung17@u.rochester.edu