Wilmot scientists exploit cell metabolism to attack cancer
Medical Center researchers have shown for the first time how cancer-causing mutations control and alter the way cancer cells biosynthesize and replicate.
Nuclear protein causes cancer to become more aggressive
Neuroblastoma is one of the most common and deadly of childhood cancers, and Medical Center researchers have discovered that aggressive forms of the cancer contain a specific protein in their cells’ nuclei not found in more benign cases.
As leukemia evolves, stem cells hold keys to newer therapies
A study from the Wilmot Cancer Institute is believed to be the first to examine how leukemia stem cells change over time, and the first to look for several known gene biomarkers simultaneously.
10 years ago: Cancer vaccine with Rochester roots approved
Largely unreported in 2006 was the remarkable story of three Rochester virologists whose innovation, dedication, and perseverance resulted in the key breakthrough that lies at the heart of the first vaccine targeting the leading cause of cervical cancer.
Right dose of walking helps chemotherapy side effects
Wilmot Cancer Institute discovered something simple and inexpensive to reduce pain and tingling in hands and feet due to chemotherapy—exercise.
Experimental therapy shrinks pancreas tumors
The results of an Wilmot Cancer Institute clinical trial for pancreatic cancer show that an experimental drug, coupled with chemotherapy, can control tumors well enough to make some patients eligible for surgery.
Wilmot Cancer Institute joins OmniSeq Genomic Network
Through this network, Wilmot Cancer Institute and Roswell Park Cancer Institute in Buffalo — the state’s two largest cancer care and research institutions outside New York City — will collaborate and expand genomic testing for cancer across the Finger Lakes and western New York region.
Scientists hand out lemonade to support national foundation
Professor Danielle Benoit and her students will be serving lemonade and explaining their work on childhood cancer therapies this weekend as part of a national effort organized by Alex’s Lemonade Stand Foundation, which has helped fund her research.
Blocking cellular quality control mechanism gives cancer chemotherapy a boost
A University team found a way to make chemotherapy more effective by exposing cancer cells to a molecule that inhibits NMD (nonsense-mediated mRNA decay) prior to treatment with doxorubicin, a drug used to treat leukemia, breast, bone, lung and other cancers.
An extra protein gives naked mole rats more power to stop cancer
Naked mole rats are small, hairless, subterranean rodents that have never been known to get cancer despite having a 30-year lifespan. A new protein discovered by biologist Vera Gorbunova may help explain why.